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Managing High Blood Pressure: Risks of Common Medications and Safer Alternatives

Dr. Kyle Benson

High blood pressure can worsen with certain common medications many adults take daily.

Understanding the Impact of Blood Pressure-Raising Drugs

Approximately one in five adults with hypertension may experience worsened blood pressure control due to the use of specific medications. These include widely prescribed antidepressants, nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen, oral steroids, antipsychotics, oral contraceptives, and decongestants. Such drugs, while effective for other health issues, can inadvertently raise blood pressure and complicate hypertension management.

Prevalence Among Hypertensive Populations

Women with high blood pressure are particularly affected, with nearly 24% taking medications that may raise blood pressure. Among men, the figure stands at around 14%. This usage pattern reflects both the prevalence of these medications for other conditions and the challenges in coordinating multi-drug regimens for patients with hypertension.

Risks Highlighted by Medical Experts

Dr. John Vitarello of Boston's Beth Israel Deaconess Medical Centre underscores the importance of recognizing these risks, especially in older adults who often experience polypharmacy—taking multiple medications simultaneously. Awareness of how certain drugs contribute to elevated blood pressure can help clinicians avoid exacerbating cardiovascular risk while treating comorbid conditions.

The Role of Polypharmacy in Older Adults

Polypharmacy increases the complexity of managing hypertension due to potential drug interactions and additive effects on blood pressure. Patients may be unaware that medications prescribed for pain relief, mental health, or other common issues are affecting their cardiovascular health. Careful medication review is essential to identify and address these hidden contributors.

Strategies for Safer Blood Pressure Management

The study advocates for deprescribing or substituting blood pressure-raising medications with safer alternatives whenever possible. This strategy involves assessing each patient’s medication profile to determine if any drugs can be discontinued or replaced without compromising treatment for other conditions. Such an approach aims to optimize blood pressure control and reduce cardiovascular risk.

Clinical Implications and Recommendations

Healthcare providers should maintain vigilance regarding medication-induced hypertension risks. Routine medication reconciliation in hypertensive patients can reveal opportunities to minimize harmful drug effects. Patient education is also vital, enabling individuals to understand how their medications affect blood pressure and encouraging open communication with their healthcare team.

Research Presented at the American College of Cardiology

These findings were shared at the American College of Cardiology's 70th Annual Scientific Session, emphasizing ongoing efforts to improve cardiovascular health through multidisciplinary collaboration. By integrating pharmacological review into hypertension management, clinicians can better tailor treatments to individual patient needs.

Incorporating knowledge about the impact of common medications on blood pressure is crucial for effective hypertension care. Identifying and managing these risks supports better cardiovascular outcomes and enhances patient quality of life.

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